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BioMart errors - Error in file.exists(file) : invalid 'file' argument + 404 hosts
biomaRt
written 20 days ago by
francisco.brito
▴ 10
6
votes
9
replies
7.4k
views
WGCNA coupled with differential expression analysis: question about baseline module detection
wgcna
WGCNA
written 6.4 years ago by
Colari19
▴ 60
0
votes
1
reply
125
views
Transcriptomic analysis
limma
FPKM
updated 1 day ago by
Gordon Smyth
54k • written 3 days ago by
Kokila
• 0
0
votes
1
reply
247
views
For bulk RNA sequencing analysis to find Immediate Early Genes, would using a shrinkage estimate like apeglm be helpful?
Bioconductor
RNASeq
updated 5 days ago by
ATpoint
★ 5.1k • written 5 days ago by
Alexis
• 0
0
votes
0
replies
114
views
Cagrilintide (CAG) Peptide: Benefits, Dosage, Side Effects, Reviews & 10mg Guide | ZyCarePeptides
healthyFlowData
healthyControlsPresenceChecker
5 days ago
jemskim0107
• 0
1
vote
2
replies
441
views
Results from the last DESeq2 version differ significantly from the previous version
DESeq2
updated 6 days ago by
Michael Love
43k • written 10 days ago by
Erandi
• 0
0
votes
1
reply
462
views
aveLogCPM() gives incorrect first-row result when offset is supplied as a full matrix
Bioconductor
edgeR
updated 2 days ago by
Gordon Smyth
54k • written 9 days ago by
RanRan
• 0
1
vote
1
reply
476
views
Convenient Combining of SingleCellExperiment Objects with Different Ranges (scATAC-seq)
SingleCellExperiment
SummarizedExperiment
GEOquery
updated 11 days ago by
Aaron Lun
★ 29k • written 20 days ago by
Dario Strbenac
★ 1.6k
0
votes
1
reply
438
views
WGCNA for a paired design study of 6 participants, microarray data, hub genes
Bioconductor
limma
removebatcheffect
updated 19 days ago by
ATpoint
★ 5.1k • written 19 days ago by
PTE
• 0
0
votes
0
replies
285
views
News:
BiocAsia 2026: Call for Workshop Proposals (Deadline: 21 Aug 2026)
BiocAsia2026
Conference
20 days ago
laurah ondari
• 0
0
votes
2
replies
2.6k
views
how to determine what kind of dispersion to use
graph
edgeR
graph
edgeR
written 12.6 years ago by
Guest User
★ 13k
23
votes
14
replies
33k
views
gene dispersion, what does it mean?
gener
rnaseq
written 10.8 years ago by
tonja.r
▴ 80
3
votes
3
replies
713
views
Using edgeR with count data from seqpac and getting outsized logFC
edgeR
20 days ago
Matthew Thornton
▴ 390
1
vote
1
reply
493
views
Job:
We are paying researchers to capture the work you are already doing!
JobPosting
job
offtopic
updated 20 days ago by
Gordon Smyth
54k • written 20 days ago by
Mihir
• 0
1
vote
4
replies
752
views
Optimizing Differential Methylation Analysis of Large Datasets Using edgeR
edgeR
DifferentialMethylation
23 days ago • updated 21 days ago
Lucas
• 0
0
votes
1
reply
1.1k
views
fit gene distribution to negative binomial
microarray
written 6.5 years ago by
fabien.tell
• 0
0
votes
1
reply
601
views
Any developer who would like to try an agent and agent skills to developing/ packaging / reviewing your current tool?
BiocCheck
biocthis
Bioc
biocViews
contribution
written 23 days ago by
Yeji
• 0
0
votes
2
replies
565
views
methylumi fails to load with lattice 0.23-1
methylumi
25 days ago • updated 22 days ago
Paul Ruiz Pinto
• 0
3
votes
1
reply
652
views
Barcode Plot for Zenodo 17114800
DropletUtils
updated 25 days ago by
Aaron Lun
★ 29k • written 28 days ago by
Dario Strbenac
★ 1.6k
1
vote
1
reply
2.6k
views
Job:
PostDoc at Novartis Oncology Basel - Intratumor heterogeneity
cancer
genomics
postdoc
job
Job
written 10.4 years ago by
Kauffmann, Audrey
▴ 60
1
vote
2
replies
805
views
Struggling in getting significant in matched pre/post proteomics
limma
updated 23 days ago by
Gordon Smyth
54k • written 26 days ago by
Nuria
• 0
2
votes
4
replies
1.4k
views
Change in values using edgeR::cpm() between RELEASE_3_22 and RELEASE_3_23
edgeR
7 weeks ago • updated 27 days ago
Stevie Pederson
• 0
0
votes
9
replies
3.2k
views
FW: Graphviz in Vista64
Rgraphviz
SIM
Rgraphviz
SIM
written 17.5 years ago by
Sim, Fraser
▴ 350
0
votes
0
replies
10
views
Spam:
U4GM Diablo 4 Guide: Gladiator's Triumph & Sigils
RAREsim
4 weeks ago
luissuraez798
0
0
votes
0
replies
6
views
Spam:
Best Diablo 4 Rogue Builds: U4GM on Gladiator's Triumph
GA4GHshiny
4 weeks ago
luissuraez798
0
0
votes
0
replies
8
views
Spam:
u4gm's poe1 Guide to Cards, Bases, and Strictness
RAREsim
4 weeks ago
luissuraez798
0
0
votes
0
replies
8
views
Spam:
Arc Raiders Phantom Targets: A U4GM Expert Review
dmrseq
4 weeks ago
luissuraez798
0
0
votes
5
replies
1.1k
views
Normalization when merging two different datasets in QFeatures
QFeatures
Normalization
updated 23 days ago by
Laurent Gatto
1.6k • written 4 weeks ago by
anna.senovska
• 0
2
votes
2
replies
932
views
Details on raw data pre-processing
curatedMetagenomicData
updated 4 weeks ago by
Levi Waldron
★ 1.1k • written 4 weeks ago by
lauracamilavega29
▴ 10
0
votes
6
replies
1.6k
views
Complicated nested model - best limma approach?
limma
updated 27 days ago by
Gordon Smyth
54k • written 4 weeks ago by
gabsjacobson
• 0
0
votes
3
replies
910
views
Preprocessing for Illumina MouseRef-8 microarray data
limma
4 weeks ago • updated 27 days ago
Gordon Smyth
54k
0
votes
0
replies
8
views
Spam:
FH6 Cars Racing Tips: Smart Upgrades by U4GM
RAREsim
GA4GHshiny
5 weeks ago
frmu12190
0
0
votes
0
replies
9
views
Spam:
U4GM Insights on Trading GAG 2 Items Wisely
GA4GHshiny
5 weeks ago
frmu12190
0
0
votes
0
replies
10
views
Spam:
U4GM's Modern Warfare 4 Loadout Strategy Guide
RAREsim
5 weeks ago
frmu12190
0
0
votes
0
replies
18
views
Spam:
Toi uu hoa xu ly du lieu single-cell RNA-seq voi dung luong RAM han che?
dmrseq
5 weeks ago
hoanvuminh830
0
2
votes
4
replies
775
views
DESeq2 shrinkage before a downstream survival screen across cohorts
Bioconductor
DESeq2
RNASeq
written 6 weeks ago by
Arjun
• 0
0
votes
1
reply
1.4k
views
GOseq Probability Weight Function bad fit
goseq
written 11 months ago by
francesca
• 0
0
votes
0
replies
11
views
Spam:
Luxury Real Estate Trends in 2026: Expert Insights for High-End Home Buyers
Devel
6 weeks ago
Almasi
0
0
votes
0
replies
389
views
DESeq2 timecourse with two additional factors, reduced design formula question for LRT test
DESeq2
timecourse
6 weeks ago
ckeeling
• 0
0
votes
0
replies
6
views
Spam:
How long does Cenforce D take to work?
RAREsim
6 weeks ago
jessicaawalkerr060
0
0
votes
0
replies
6
views
Spam:
What Documents Are Needed for Intellectual Property Registration in Dubai?
dmrseq
6 weeks ago
Albert
0
0
votes
1
reply
1.2k
views
How to start learning RNA sequence analysis with DESeq2
DESeq2
updated 6 weeks ago by
Michael Love
43k • written 6 months ago by
Syed
• 0
0
votes
3
replies
1.1k
views
Changing reference level influences DESeq2 results
DESeq2
updated 6 weeks ago by
Michael Love
43k • written 7 weeks ago by
andrewsiefert
• 0
1
vote
2
replies
4.1k
views
BiocManager::install("EnsDb.Hsapiens.v75") install fails with non-zero exit status
biocmanager
Install
written 5.6 years ago by
saadmurtazakhan
▴ 10
0
votes
5
replies
2.5k
views
Help on factorial experiment analysis using limma
limma
limma
written 23.0 years ago by
Yuk Fai Leung
▴ 100
1
vote
2
replies
1.1k
views
removeBatchEffect(): Preserving a continuous biological variable that differs across batches
limma
RNASeq
7 weeks ago
Vinesh
• 0
1
vote
0
replies
1.8k
views
News:
Annual Nominations Open for CAB and TAB! Deadline Aug 31 2026
Bioconductor
TAB
CAB
8 weeks ago
Maria Doyle
▴ 120
0
votes
1
reply
679
views
impute installation fails due to old Fortran features in code
impute
updated 9 weeks ago by
ATpoint
★ 5.1k • written 9 weeks ago by
payerle
• 0
1
vote
4
replies
1.3k
views
Unable to install AnnotationHub
AnnotationHub
written 9 weeks ago by
Gerhard Thallinger
▴ 180
0
votes
7
replies
4.8k
views
Can Differential Isoform expression analysis can be performed using DESeq2 package
RNASeqData
isoform
DESeq2
updated 10 weeks ago by
Michael Love
43k • written 4.4 years ago by
priyanka.m
• 0
46,892 results • Page
1 of 938
Recent ...
Replies
Comment: Difference in Predictive component of PLS and OPLS Model
by
kalvindavid
• 0
In PLS-DA, the predictive component is generally reconstructed from the predictive scores, loadings, and residual structure, such as \(X = …
Comment: Differential expression of FPKM from RNA-seq data using limma and voom()
by
Gordon Smyth
54k
No, you cannot analyse differences in FPKM without doing DE analysis. It is, by definition, the same thing.
Comment: Differential expression of FPKM from RNA-seq data using limma and voom()
by
Gordon Smyth
54k
limma-trend on logCPM is nearly the same as limma-voom on raw counts, unless the library sizes are very different. I have told you what wi…
Comment: Error message from protein coding prediction with VariantAnnotation
by
Viller
• 0
When using VariantAnnotation with a non-reference genome, the overall approach of creating a TxDb from your own GFF, defining matching Seqi…
Comment: Gviz Color Filling
by
kalvindavid
• 0
A likely issue is that Gviz does not necessarily preserve the original row order when creating the GeneRegionTrack, so the color values may…
Votes
Answer: BioMart errors - Error in file.exists(file) : invalid 'file' argument + 404 host
Answer: BioMart errors - Error in file.exists(file) : invalid 'file' argument + 404 host
BioMart errors - Error in file.exists(file) : invalid 'file' argument + 404 hosts
A: Appropriate explanation of the methodology behind arrayWeights function from lim
Comment: Ensembl 116 / Ensembl Genomes 63 have been released - a milestone for BioMart
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