Our ancestors emerged on a primitive Earth that lacked oxygen. @ishahjain, @AyushDMidha, and team found a surprising way that we still use their coping strategies today.
Science Fellow @zhou_jingtian builds single-cell and computational frameworks to probe the 3D genome. His work tells us more about how the epigenome and transcriptome interact to shape cell state and complex disease:
Nearly 300 teams have already submitted to the Virtual Cell Challenge leaderboard to see how their initial models rank on this year’s six metrics.
Here’s the current standing:
The 2026 Virtual Cell Challenge has begun! Submissions and the leaderboard are now open.
This year's task: multi-context generalization and zero-shot prediction. Models will need to predict perturbation responses in cellular contexts with no Challenge-specific training data.
Evolution builds genes by recombining domains from existing ones. Innovation Investigator @Roth_Lab and colleagues introduce DESynR, a platform that does this on demand, creating new genes that outperform their natural counterparts in human CAR T cells.