JCI insight

@JCI_insight

High-quality basic & translational research representative of biomedical specialties & physician-scientists. Bluesky: bsky.app/profile/insigh…

insight.jci.org

Joined October 2016

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JCI insight
@JCI_insight
Sep 8
The gene-environment interplay is important for the development of asthma: doi.org/10.1172/jci.in… The cover image features work by Otoshi et al. @ColumbiaMed, reporting on how the genetic background and retinoid micronutrient perturbations influence the lung developmental
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JCI insight
@JCI_insight
17h
🧵 Dysregulation of UGDH is associated with tumorigenesis in #BreastCancer: doi.org/10.1172/jci.in… Price et al. @DukeMedSchool find genetic knockdown of UGDH blunts estrogen-stimulated breast cancer phenotypes in vitro, ex vivo, and in vivo, irrespective of estrogen receptor
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JCI insight
@JCI_insight
Sep 7
Could platelets serve as a therapeutic target in alcohol-associated hepatitis? doi.org/10.1172/jci.in… Matthew J. McConnell @mcconnell_md & team @YaleMed report platelets upregulate inflammatory mediators in alcohol-associated hepatitis that can contribute to liver inflammation.
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JCI insight
@JCI_insight
Sep 6
This week's highlight💫: This proteomic score outperforms widely used clinical risk models for major adverse cardiovascular events among individuals with diabetes: doi.org/10.1172/jci.in… Svati H. Shah @SvatiShah & team @DukeMedSchool report on blood proteins that help predict
JCI insight
@JCI_insight
Sep 5
Saturday Special💫: 🧵 Welcome to the kidney! doi.org/10.1172/jci.in… R. Ariel Gomez & team @MedicineUVA use high-resolution 3D imaging to examine the role of renin cells in renal neurovascular morphogenesis and remodeling. They found renin cells closely interact with nerves to
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