The DiffUSE Project

@diffUSEproject

Infrastructure for learning and representing protein motions from structural data

Pinned
The DiffUSE Project
@diffUSEproject
Mar 12
Open data. Public logbooks. No waiting for publications. The DiffUSE Project is redesigning the structural biology pipeline from sample prep to modeling, all in the open. Meet DiffUSE: youtu.be/_DILlMou1GM?si…
The DiffUSE Project
@diffUSEproject
Sep 4
Diffuse scattering is hard to compare quantitatively across experiments, let alone across synchrotrons. A new DiffUSE Project update shows diffuse maps reproducing across CHESS and ALS. Read the project update: diffuse.science/posts/reproduc…
The DiffUSE Project
@diffUSEproject
Sep 3
Diffuse scattering can encode correlated protein motions, but standard pipelines often discard it as background. mdx2 is an open-source Python toolkit for carrying that signal through processing. Read @meisborg.bsky.social's overview and try mdx2: diffuse.science/posts/mdx2/
The DiffUSE Project
@diffUSEproject
Sep 1
Same mission, but an expanded vision for revolutionizing structural biology to better capture protein motion. Launching September 8.
The DiffUSE Project
@diffUSEproject
Aug 28
Check out our latest! 🌊
Stephanie Wankowicz
@stephanie_mul
Aug 27
New pub from @diffUSEproject! Ordered water molecules mediate protein stability, ligand binding, and catalysis. Predicting them has lagged behind protein structure prediction. We developed WaterFlow, a new state-of-the-art method for placing ordered water. biorxiv.org/content/10.648…