🫀 The 4 pillars of #HFrEF therapy don't overlap….they STACK
ARNI + BB + MRA + SGLT2i vs no meds:
📉 ~61% ↓ death (HR 0.39)
➕ +6 life-years (vs ACEI+BB)
Distinct pathways = additive benefit
Not hype: 2 independent meta-analyses agree (Tromp 0.39 ≈ Vaduganathan 0.38)
