Congratulations to Arindam Datta @arindam_datta1 on publication of “The BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells”.
The Greenberg lab investigates processes that affect genome integrity and how they influence human biology
- Thrilled to announce that postdoc, Haoyang Jiang, has been awarded an NCI Pathway to Independence Award (K99/R00) for his project, "BLM-Driven Recombination at Alternative Lengthening of Telomeres and Non-Telomeric Sites." Congratulations Haoyang on this well deserved award!
- Great work in Mol Cell from John Maciejowski's group delineating BAF dependent regulation of TREX1 and cGAS in micronuclei. Very important implications for immune responses to chromosome instability. cell.com/molecular-cell…
- Please see our review article in NSMB, “Mechanisms and genomic implications of BIR”. Adel Atari and @HaoyangJiang2 focus on mammalian BIR, its relationships to human disease, and genome engineering. Thanks to reviewers for helpful comments. nature.com/articles/s4159…
- Please see our discovery of first-in-class BRISC deubiquitylating enzyme inhibitors rdcu.be/edRwF. A great journey with Elton Zeqiraj, Francesca Chandler, Joe Salvino. High-throughput screens, cryo-EM structure and ontarget activity to reduce inflammatory signals.

