In a series of 3 papers and preprints, we’re thrilled to share with you the working laser phase plate. In collaboration with research led by Holger Müller at UC Berkeley, this is a huge innovation in imaging to make small and faint objects inside cells visible.
.@alexrives, our Head of Science, and the Biohub team have been named to @TIME's TIME100AI list for 2026.
Alex is shaping our work at the frontier of AI and biology, including ESM, our world model of protein biology, and the data to build frontier models through our labs and the
Tumors aren't one disease—they're patchworks of coexisting cancer cell states, each with its own survival strategy. That's why a single drug often can't keep the disease from coming back.
Across two new Nature Genetics papers, we used AI (ARACNe + VIPER) to map these states, and
New in @CellCellPress: 15 grand challenges for the field of AI-accelerated biology, inspired by a famous list of 23 math problems created by mathematician David Hilbert. Co-authored by Biohub’s @ShanaOKelley and @califano_lab.
Predicting protein structure directly from sequence—no MSA required.
Join us Aug 25 at 1pm PT for a webinar on ESMFold2, our open-source structure prediction model. We'll cover the science behind the model, then give a hands-on demo of how to fold proteins and biomolecular