Eterna

@eternagame

Eterna is a videogame where you can invent medicine. You solve RNA design puzzles, and your solutions get synthesized and tested by biochemistry & robotics!

Stanford, CA

eternagame.org

Joined October 2010

Eterna
@eternagame
Aug 7
Our Replicase pilot results found that the catalytic activity and copyability of the 71-89 polymerase ribozyme can be improved! We have launched a new puzzle for finding a version that excels at both properties simultaneously. Comp methods are encouraged to submit designs!
Eterna
@eternagame
Aug 6
Major props @DidiKieran @jgkoob @lemerleau @IIMCB_Poland @FrankRHutter @AF_Panescu @chaitjo @rishabh16_ for generating 600,000 sequences to fold into 1000 synthetic pseudoknots! The wet lab results will help these researchers improve their computational methods for RNA design.
Eterna
@eternagame
Jul 23
OpenKnot Round 9 features secondary structures designed by players to create compact, pseudoknotted RNA using 240 bases. GenAI teams also will test whether their methods perform as well as the expert players at a longer length. Check out the puzzle at: eternagame.org/labs/14343053
Eterna
@eternagame
Jul 23
OpenKnot Round 9 features secondary structures designed by players to create compact, pseudoknotted RNA using 240 bases. GenAI teams also will test whether their methods perform as well as the expert players at a longer length. Check out the puzzle at: eternagame.org/labs/14343053
Eterna
@eternagame
Jul 17
Eternacon 12 will be Sunday, July 26, 9am to 2pm PT featuring talks on player pseudoknot design techniques, the Montparnasse algorithm solving the Eterna100, an RNA scaffold for cryo-EM, and results for our pilot Replicase puzzle. Free to register at eternagame.org/eternacon/2026
Eterna
@eternagame
Jul 7
Eterna's newest puzzle challenges players to design 240-base RNA strands that will fold into compact pseudoknots. The puzzle provides a metric for counting the number of pairs that cross to form large, synthetic pseudoknots. Check out the puzzle at eternagame.org/labs/14333719