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Comment: Complicated nested model - best limma approach? by Gordon Smyth 54k
I don't recommend imputation at all, as the limpa package approach is preferable and doesn't need imputation. If you do impute however, th…
Comment: Complicated nested model - best limma approach? by gabsjacobson • 0
Thank you. Do you recommend normalizing (here I used limma::normalizeBetweenArrays(method="scale") before or after imputation?
Comment: Normalization when merging two different datasets in QFeatures by anna.senovska • 0
Hi Laurent, thanks for the input. The EVs dataset contains 7000 proteins, cells dataset 9000 proteins. They share 6000 proteins.
Comment: Normalization when merging two different datasets in QFeatures by anna.senovska • 0
thanks Gordon, I will check it out
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Details on raw data pre-processing
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