Find Reactions, Proteins and Pathways
Pathway Browser
Visualize and interact with Reactome biological pathways
Analysis Tools
Merges pathway identifier mapping,
over-representation, and expression analysis
AI Chatbot
Meet the React-to-Me AI Chatbot! Designed to answer your questions about Reactome Pathways.
ReactomeFIViz
Designed to find pathways and network patterns related to cancer and other types of diseases
Documentation
Information to browse the database and use its principal tools for data analysis
Reactome Research Spotlight
[July 5th, 2026] In their April 2026 PLOS Computational Biology education article“ Ten common mistakes that could ruin your enrichment analysis ”, Bora et al. identify ten methodological pitfalls that undermine functional enrichment analysis in published research, and explicitly recommend Reactome as one of the few comprehensive pathway databases whose breadth, currency, and built-in tools directly address many of them.
Why Reactome
Reactome is a free, open-source, curated and peer-reviewed pathway database. Our goal is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modeling, systems biology and education.
The development of Reactome is supported by a grant from the US National Institutes of Health (U24 HG012198).
Version 97 released on June 30, 2026
Human Pathways
Reactions
Proteins
Small Molecules
Drugs
Literature References
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API and Data access
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