Jason Locasale (@LocasaleLab) / X

Jason Locasale

4,196 posts

Jason Locasale

@LocasaleLab

Scientist and professor. Follow for science, health, and academic reform. DMs open • dr.jason.locasale@gmail

Raleigh, NC

scholar.google.com/citations?user…

Joined March 2015

Pinned
Jason Locasale
@LocasaleLab
Jul 8
I’m collecting my longer takes and formatting them into more complete essays on Substack. They go deeper than what fits on X, and the bigger themes will be collected in one place: science reform, academia, biomedical and health science, public trust, and the future of scientific
Rebuilding science | Jason Locasale | Substack
From rebuildingscience.substack.com
Jason Locasale
@LocasaleLab
Nov 10, 2025
I am actually the lead and corresponding author on the most cited research paper of this person's career. Someone told me that today, and I verified it. The claim that her work has had any substantial effect on breast cancer is a dramatic overstatement. Like much of what’s
60 Minutes
@60Minutes
Nov 10, 2025
Harvard researcher Joan Brugge says her work has the potential to prevent breast cancer, but she was notified last spring that her federal funding was terminated. “It was just like a gut punch. My knees buckled, and I had to sit down,” she says.
00:00
Jason Locasale
@LocasaleLab
Sep 22, 2025
This is an absurd take. Yes, H-1Bs are necessary in some fields and abused in others, but let’s be clear: the AMA is the very organization that gatekeeps the supply of doctors. Of course they want to posture on this issue. I’ve known countless students who would have been fine
AMA
@AmerMedicalAssn
Sep 22, 2025
Raising the H-1B visa fee to $100,000 risks shutting off the pipeline of highly trained physicians, especially in rural and underserved communities. The AMA stands ready to work with the administration and our partners in medicine to exempt health care workers from this policy,
Jason Locasale
@LocasaleLab
Nov 11, 2025
Replying to @stuartbuck1 and @jaypgreene
I said research paper. The ones above it are literature reviews or laboratory methods papers, not original research. In the sciences there is a big distinction between original work and literature review.
Jason Locasale
@LocasaleLab
Jul 18, 2025
I went into academia to search for truth. I left learning how to write safe grants, avoid controversy, and serve bureaucrats.
Jason Locasale
@LocasaleLab
Oct 1, 2025
In the Duke lacrosse scandal, the accuser later went to prison, the DA was disbarred for misconduct - but the Duke administrator at the center was promoted, her role downplayed despite serious allegations in the players’ lawsuit. She went on to have a thriving career at Duke and
Yuri Bezmenov Subversion
@yuribezmenov22
Oct 1, 2025
Replying to @christopherrufo
Duke lacrosse hoax showed that nothing changed because no one was held accountable
Jason Locasale
@LocasaleLab
Nov 10, 2025
Replying to @60Minutes
I am actually the lead and corresponding author on the most cited research paper of this person's career. Someone told me that today, and I verified it. The claim that her work has had any substantial effect on breast cancer is a dramatic overstatement. Like much of what’s
Jason Locasale
@LocasaleLab
Oct 30, 2025
This resonates. The Harvard undergrads who worked with me were often the least capable researchers — not because they lacked intelligence, but because they’d never learned to focus deeply on one thing. They treated research like another extracurricular, always chasing a new club,
Steve McGuire
@sfmcguire79
Oct 30, 2025
These Harvard students…did not react well to the report on grade inflation: “The whole entire day, I was crying. I skipped classes on Monday, and I was just sobbing in bed because I felt like I try so hard in my classes, and my grades aren’t even the best. It just felt
Jason Locasale
@LocasaleLab
Sep 1, 2025
RFK Jr. is being maligned by the establishment and legacy media for the turmoil at the CDC, but the real story is simpler. The CDC resisted ACIP’s attempts to review fundamental questions about vaccine safety and efficacy. These aren’t fringe concerns. They’re the kinds of
Jason Locasale
@LocasaleLab
Sep 29, 2025
A shameful reminder of how quickly universities throw people in the trash. John Searle passed away. He was one of the most influential philosophers of his era who theorized about the nature of AI. He was discarded by UC Berkeley after false metoo accusations. His legacy was
Jason Locasale
@LocasaleLab
Oct 30, 2025
A friend from academia, someone I haven’t spoken to in years, saw my account and reached out privately. They asked to stay anonymous but wrote: “Of course I agree with what you say. Anyone with a head on their shoulders would agree. The question is, where did all the reasonable
Jason Locasale
@LocasaleLab
Aug 12, 2025
Still think this is just a campus humanities thing? The previous Director of the NIH - in charge of $50B in science funding - makes ideological claims about gender identity in 5-year-olds in Feb 2025. This runs from the ivory tower straight into the highest levels of the federal
Jason Locasale
@LocasaleLab
Aug 19, 2025
Now he speaks - only when the checks stop clearing. Where was this outrage when the institutions were rotting from within? The grants were never yours; they’ve always belonged to bureaucracies that long ago stopped serving science. "Academic freedom" has been an illusion for
Martin Bauer
@martinmbauer
Aug 18, 2025
Terence Tao: "This is not a routine policy shift - it is a deliberate dismantling of the institutions, funding, and freedoms that have sustained American science for generations."
Jason Locasale
@LocasaleLab
Nov 2, 2025
The majority of PhDs I’ve seen at top schools showed little true passion for research. Most were there for other reasons - immigration pathways, career credentials, networking, or simply a comfortable position with modest responsibilities. Increasingly, many drifted into campus
Derya Unutmaz, MD
@DeryaTR_
Nov 1, 2025
Correct. Earlier this year, I also said we should reduce PhD positions by at least half & shorten completion time. Only the most passionate should pursue a PhD. In the age of AI, steering many others toward this path does them a disservice given the significant opportunity costs.