.@samjlord @KatrinaVelle @MullinsLab & @FritzLaylin propose a simple way to highlight both experimental #reproducibility and cell-to-cell variation, while avoiding pitfalls common in analysis of cell biology data. bit.ly/2SdOoeG
Journal of Cell Biology
16.1K posts
Journal of Cell Biology
@JCellBiol
The Journal of Cell Biology (JCB) publishes peer-reviewed research on all aspects of cellular structure and function. Est. 1955 - @RockUPress
- .@kat_shkarina, @broz_lab @unil and colleagues report the development and characterization of a new optogenetic toolset for #apoptosis, #necroptosis, and #pyroptosis induction in humans, mice, and #zebrafish. bit.ly/3jBVV4a #CellDeath #optogenetics #Immunology
00:00 - .@EvaMariaWenzel, @harald_stenmark et al. review how the endoplasmic reticulum controls the positioning, dynamics, & functions of other #organelles via membrane contact sites. bit.ly/3dhW9Or Part of our #Lipid and #Membrane Biology collection: bit.ly/3D9emaf
- New work from @Charlie_R_Bond & @Melike_Lak et al offers multiplexed DNA-PAINT super-resolution pipeline for investigating #organelle heterogeneity with single organelle resolution, identifying up to 8 subsets of late #endosomes/#lysosomes in a single cell hubs.la/Q02WCK_P0
- Takami Sho, Li Yu et al. @Tsinghua_Uni unveil migratory autolysosome disposal, a response to #lysosome damage where cells expel LAMP1-LC3 positive structures via autolysosome exocytosis, requiring #autophagy machinery, SNARE proteins, and cell #migration. hubs.la/Q02Rwbhg0
00:00 - This poster-as-DM-thread from Jimmy Hsu in @GaryBrouhard ’s lab has got to be the most innovative poster idea I’ve seen! And it’s not just a gimmick - it clearly communicates some really cool science about microtubule dynamics. (Photo poster with permission.) #mweJCB #ASCBEMBO19
- Wenzel, Elfmark, Stenmark, and Raiborg @Oslounivsykehus review how the endoplasmic reticulum controls the positioning, dynamics, and functions of other #organelles via membrane contact sites. bit.ly/3dhW9Or #ER_literature #Biochemistry #Trafficking #Metabolism
- We are pleased to introduce the members of the 2024 JCB Early Career Advisory Board. This initiative serves the journal’s ongoing goal to be representative of and responsive to every part of the cell biology community. hubs.ly/Q02dg_jq0
- .@XiaoLinichd, Gamuyao, @chiluncellbio et al. @stjuderesearch engineer a #LipidDroplet (LD)-targeting motif and develop a tool kit that can track contact sites between LDs and other organelles in living cells. hubs.la/Q02F1yfK0 @Daniel_Stabley @alexcarisey @agtebo
- Using live imaging, optogenetics, & laser-induced tight junction injury, @saranya_raajan, Ann Miller et al @UMich_MCDB show that mechanosensitive channel-dependent calcium flashes promote sustained local activation of RhoA and tight junction repair bit.ly/3J2J0Dq
00:00 - .@BruceLaneGoode, Eskin and @sshekhr review our current understanding of the cellular machinery and mechanisms driving actin network remodeling, disassembly, and turnover. bit.ly/3QWk0EE #Cytoskeleton #Biochemistry
- JCB is pleased to present a special collection highlighting recent papers on the mechanical properties of cells and tissues, and the application & transmission of forces across scales relevant to cell biology. Gain new insights into #mechanobiology 👉 bit.ly/3sMxtF9
- Image shows accumulation of mtDNAs in the cytosol stimulates the cGAS-STING-mediated immune response. In this review, Sookyung Kim, Theresa Ramalho, and @chaynes329 discuss how #mitochondria-to-nuclear communication promotes #proteostasis and #immunity. hubs.la/Q02kwK-N0
- Tight junctions regulate the mechanical resistance of epithelial cell junctions. @tann_nguyen, @tetsuotani1, Mikio Furuse et al. show that cell junctions fracture upon cell stretching in cells lacking TJ membrane proteins claudin, JAM-A, and CAR. hubs.la/Q02qqN3H0
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