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Our latest in @molpsychiatry: In patients with anxiety+depression, targeting a novel “anxiosomatic” circuit in dmPFC outperforms standard dlPFC target for anxiety, and equally effective for depression.
nature.com/articles/s4138…
Shan Siddiqi @shansiddiqi.bsky.social
2,411 posts
Shan Siddiqi @shansiddiqi.bsky.social
@shansiddiqi
Brain hacker | Causal🧠 stim target mapper | Neuropsychiatrist @HarvardMed | ❤️@AaishahRaquib, twin turbos, blitz♟️, blues🎸
- Unpopular opinion: I love my job. I love psychiatry, I love neuroscience, I love academia, my patients (but not their insurance company), my students, MATLAB, and maybe even Reviewer 2. Just wanted to balance the seemingly-opposing viewpoints that seem to be all over Twitter.
- Replying to @designmomAs a psychiatrist, I’ve seen a situation in which CPS in Boston tried very hard to do something similar to one of my patients. I had to fight with an aggressive CPS worker who clearly had a vendetta and was making false statements about the patient’s psychiatric condition.
- Out now in @BiologicalPsyc1 @SOBP Our latest thoughts on "Targeting symptom-specific networks with TMS," with @foxmdphd of @BWHNeurology Thanks to @harvardbrainsci @BrighamResearch @Brain_Circuits biologicalpsychiatryjournal.com/article/S0006-…
- Out now in @NatureHumBehav @SpringerNature: TMS, DBS, and lesions converge on common causal circuits in neuropsychiatric disease. Lesions reveal better TMS/DBS targets. All 3 modalities can modulate similar circuits. Thanks @foxmdphd and 24 co-authors! rdcu.be/cnZQ1
- Just changed my email signature from "Instructor" to "Assistant Professor." Let's also make it Twitter official.
- Out now @NatureHumBehav w/Joe Taylor, @foxmdphd A common brain network unites heterogeneous published atrophy sites across mental illness Surprisingly, lesions to the network led to DECREASED mental illness, suggesting it's compensatory, not causal rdcu.be/c3i5r
- Check out our latest thoughts on translating recent innovations into concrete approaches for targeting brain circuits clinically. In @npp_journal #NPPR2024 With @foxmdphd @RolstonJohn @Khosravan2Sanaz @BWHNeurology @BWHNeurosurgery @harvardbrainsci
- Our latest work, out now in @ScienceTM Precision fMRI mapping reveals distinct connectivity patterns for depression associated with traumatic brain injury science.org/doi/10.1126/sc… A brief explainer thread (1/n) Thanks to co-authors @DavidLBrody1 @leuthardt @MauCorbetta + more
- NEW @NatRevNeurosci Causal Mapping of Human Brain Function We propose a structured framework, synthesizing great thinkers in theology, philosophy, econometrics, microbiology, epidemiology, computer science, and even neuroscience Thanks @foxmdphd @josef_parvizi @KordingLab 1/nCausal mapping of human brain function: New review paper with @shansiddiqi, @josef_parvizi and Michael D. Fox nature.com/articles/s4158…
- I wonder if my paper would have a better shot at Nature Neuroscience if I referred to my patients as "primates."
- I think psychiatry is mostly about treating diseases that haven't been discovered yet ...and psychiatric neuroscience is mostly about discovering them and handing them over to the neurologists.
- Out now in @BiologicalPsyc1: Individualized TMS site connectivity predicts antidepressant efficacy. We independently replicated recent work by @cashmachine15, @PBFitzgerald, and @AndrewZalesky. Thanks to co-authors/mentors @alvaropleone and @foxmdphd! authors.elsevier.com/a/1crDK1S07ieh…
- I think we settled the debate about whether neuroanatomy of MS lesions is related to depression risk in a large sample (n=281). Peak in VTA. Excited to share our new paper @NatMentHealth with @IsaiahNeurology @foxmdphd @harvardbrainsci @BrighamResearch nature.com/articles/s4422…
Excited to share - we identify a unique #MS #depression circuit by analyzing the connectivity of MS lesion locations. Possible #TMS target? @shansiddiqi @foxmdphd @BWHNeurology @Brain_Circuits @NatMentHealth Brigham MS Center nature.com/articles/s4422…
