Analysis of Renal Stones by FT-IR Spectroscopy: A Helpful, Simple and Accurate Tool | Chapter 02 | Emerging Research in Medical Sciences Vol. 3
Aims: To investigate, by infrared spectroscopy (FT-IR), the chemical composition of urinary calculi obtained from patients of Buenos Aires, Argentina. Duration of Study: The composition of the urinary calculi was evaluated in a retrospective study from March 1993 to December 2018. Methodology: Infrared spectra of the urinary calculi were recorded in a Bruker IFS-25 FT-IR, Bruker Alpha-T and in a Nicolet 380 FT-IR spectrophotometers. We included 542 urinary stones (331 from men and 211 from women). The samples were obtained by spontaneous passage, shockwave lithotripsy, ureteroscopy or percutaneous nephrolithotripsy. Results: Calcium oxalate (both in pure or mixed samples) was detected in 396 cases (73.06%). Anhydrous uric acid and struvite+apatite (7.56%) were both observed most frequently, followed by carbonate apatite + amorphous Ca-phosphate (2.58%) and cystine (2.03%). For some chemical compounds, a significant gender-related difference was found. Applying the seco...
