Little Iodine was an American Sunday comic strip, created by Jimmy Hatlo, which was syndicated by King Features and ran 1943 until 1985. The strip was a spin-off of They’ll Do It Every Time, an earlier Hatlo creation.
First seen during the 1930s in a supporting role in Hatlo’s popular gag panel, They’ll Do It Every Time, Little Iodine was the daughter of Henry Tremblechin and his wife, Cora. Her purpose was to serve as a pesky nuisance to the strip’s star, Henry, and her behavior caused endless misery for her mild-mannered, easily unsettled father.
However, Iodine proved to be popular in her own right, stealing the strip from her parents, so Hatlo promoted the character into her own strip in 1943. Iodine’s antics gave the Sunday comics page a female precursor to Hank Ketcham’s Dennis the Menace. From 1943 to 1963, Little Iodine was written and drawn by Hatlo, who said, “I tried to make her the embodiment of all the brats I knew… I tried to make her naughty as hell—and still likable.”
Al Scaduto also contributed to the strip in 1966, with Hy Eisman and Bob Dunn taking the strip from 1967 through its end in 1985. Iodine also appeared in a series of 56 Dell Comics between 1949 and 1962.
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UPDATE 17-07-2025
Little Iodine 14x
Thanks to tzlovesmusic and Clark Kent
Little Iodine 1949 Incomplete
Little Iodine 1950
Little Iodine 1951 Incomplete
Little Iodine 1952
Little Iodine 1953
Little Iodine 1954
Little Iodine 1955
Little Iodine 1956
Little Iodine 1957
Little Iodine 1958
Little Iodine 1959
Little Iodine 1960
Little Iodine 1961
Little Iodine 1962
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UPDATE 26-01-2025
Thanks to Eddie Drueding
Little Iodine (1953 Sundays)
Little Iodine (1954 Sundays)
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UPDATE 06-08-2022
Little Iodine 1959 Sundays
Little Iodine 1960 Sundays
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30 pages/strips Little Iodine Various
Newspaper Comic Strips 
