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malhar
Origin
50 posts
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malhar
Origin
@malhar317
cto @origin_bio, @ycombinator, prev: uiuc cs @siebelschool
San Francisco
Joined July 2023
924
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1,133
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  • Pinned
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    malhar
    Origin
    @malhar317
    Feb 5
    Cell and gene therapies have the potential to offer a much higher quality of life to patients. Getting transcriptional control right is going to unlock a whole new class of them. Happy to share a small preview into Axis’ ability to design novel regulatory DNA sequences. It’s so
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    00:53
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    Y Combinator
    @ycombinator
    Feb 4
    Origin (@origin_bio) is using AI to make safer cell & gene therapies for diseases like cancer. Their model designs DNA switches & dials to program precise gene expression patterns in disease cells. Congrats on the launch @YashRathod_75 and @malhar317! ycombinator.com/launches/PMG-o…
    11K
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Excited to share what we’ve been working on these last few months. We’re a small team with diverse backgrounds - one of our earliest members worked on video games at a AAA studio, and our most recent is a USABO medalist. We’re looking for talented people who have worked on all
    user avatar
    Origin
    @origin_bio
    Oct 8, 2025
    Introducing Axis: the first AI model that generates regulatory DNA elements and predicts their function. Gene therapies suffer from poor efficacy, toxicity & specificity. Models like Axis can help overcome such risks. Axis beats Google DeepMind's AlphaGenome at predicting
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    25K
  • user avatar
    malhar
    Origin
    @malhar317
    Dec 9, 2024
    Image
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    roon
    @tszzl
    Dec 8, 2024
    why were so many so thoroughly persistently wrong about deep learning? it’s certainly not technical skill because many luminaries didn’t believe in it
    4.7K
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @aparanjape and @origin_bio
    Thank you!!
    101
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @abhish18 and @YashRathod_75
    Thank you!!
    77
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @nikitatr1 and @YashRathod_75
    💙
    108
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @qamcintyre
    Thanks Quinn!
    78
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @ishaans22
    Current United clears
    58
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 24, 2025
    Replying to @ishanjmukherjee and @pdhsu
    thank you!
    84
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @philip_bogdanov
    Thanks Philip!
    91
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @thereal_akashab
    Thanks Akash!
    89
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @allenainie and @YashRathod_75
    Thanks for all your help Allen :)
    61
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 8, 2025
    Replying to @Almondgodd
    Thanks Anand!
    66
  • user avatar
    malhar
    Origin
    @malhar317
    Oct 9, 2025
    Replying to @SolidlySheafy @origin_bio and @YashRathod_75
    Thanks Ben :)
    90

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